2014;220(1–2):11–9. The importance of ‘personality/temperament’ was raised in most interviews, and was often particularly valued by carers themselves. PubMed Google Scholar. Qualitative interview study with 34 individuals and 8 couples who care for a person with schizophrenia/schizoaffective disorder. Understanding the full range of treatment outcomes important to people with schizophrenia and their carers is key for ensuring that clinical practice, research and assessment are aligned with patient and carer priorities [4, 21]. However, it could also be argued that there are other means of reducing patients’ fear, distress, or pain, aside from by symptom resolution, and thus outcome measures could benefit from assessing the extent to which treatments help to reduce a patient’s experience of these negative states. Assessing the Relationship between Performance on the University of California Performance Skills Assessment (UPSA) and Outcomes in Schizophrenia: A Systematic Review and Evidence Synthesis. Objectives. 2011;37(1):29–37. Leucht S, Tardy M, Komossa K, Heres S, Kissling W, Salanti G, Davis JM. (DOCX 12 kb). Insight in psychosis: relationship with neurocognition, social cognition and clinical symptoms depends on phase of illness. Methods. Interviews were transcribed verbatim and analysed by a thematic framework based approach. Medication adherence and long-term functional outcomes in the treatment of schizophrenia in usual care. 2002;53(6):724–9. Using two regions in the same subject to identify disease-relevant gene expression differences was novel and reduced intersubject heterogeneity of findings. Or an existing research area that has been overlooked or would benefit from deeper investigation? Skeptics remain, though, and more research must be done to determine the long-term effectiveness of this type of new schizophrenia treatment. All participants gave written informed consent. http://creativecommons.org/licenses/by/4.0/, http://creativecommons.org/publicdomain/zero/1.0/, https://doi.org/10.1186/s12888-017-1418-8. Should psychosocial treatment for schizophrenia focus on the proximal or distal consequences of the disorder? The influence of temperament and character on functioning and aspects of psychological health among people with schizophrenia. Bullock WA, Young SL. Submit your article Guide for Authors. JL and HL conducted the interviews and led the data analysis. Conclusion. 2017;63(2):139–50. The Prevalence and Correlates of Social Anxiety Symptoms among People with Schizophrenia in Ethiopia: An Institution-Based Cross-Sectional Study. Results. Loganathan S, Murthy SR. This is consistent with the observation that traditional social functioning measures may not be relevant to people with severe disabilities related to schizophrenia [35], and with carers’ comments about reduced potential and lowering of expectations. These aspects are analyzed across key regions of the globe thus portraying a global perspective of the schizophrenia treatment market. This could help professionals to gain a fuller understanding of how a given treatment programme is impacting on the individual’s level of fear and distress. 2006;32(2):214–9. 1993;163:177–82. Jin H, Mosweu I. From carers’ references to a range of key developmental/life events such as moving out of the family home, getting a job, learning to drive, and having a romantic relationship, we identified ‘reaching life milestones’ as an important and novel outcome. School of Psychology, Sport and Exercise, Staffordshire University, Stoke on Trent, UK, Peninsula Medical School, Plymouth University, Plymouth, Devon, UK, Nuffield Department of Population Health, University of Oxford, Old Road Campus, Oxford, OX3 7LF, UK, You can also search for this author in [45]). Matza LS, Phillips GA, Revicki DA, Ascher-Svanum H, Malley KG, Palsgrove AC, Faries DE, Stauffer V, Kinon BJ, George Awad A, Keefe RSE, Naber D. Validation of a clinician questionnaire to assess reasons for antipsychotic discontinuation and continuation among patients with schizophrenia. Rosenheck R, Stroup S, Keefe RS, McEvoy J, Swartz M, Perkins D, Hsiao J, Shumway M, Lieberman J. The concept of ‘social acceptability’ was raised in most interviews, i.e. Kirkpatrick B, Fenton WS, Carpenter WT Jr, Marder SR. Duration of illness of the patients discussed ranged from 2 to 20+ years, with a modal duration of 11–15 years (42%). ‘The worst time that we've had was… when he was so unwell he didn’t go out the house for a year’ [C24]. ‘He can rationalise…although he hears the voices he has a sense of reality.’ [C40]. Despite intensive research, the treatment of schizophrenia is still not possible. An institution-based cross-sectional study was conducted at Amanuel Mental Specialized Hospital in Addis Ababa, Ethiopia. Simple and multiple linear regression analysis models were fitted, and the adjusted unstandardized beta (β) coefficient at 95% confidence interval was used. While the importance of physical activity for persons with schizophrenia is recognised within the literature [30], and low levels of physical activity have been demonstrated empirically to be associated with poorer outcomes in schizophrenia [31], its importance as a treatment outcome is not expressed in existing outcome measures. The consumer recovery outcomes system (CROS 3.0): assessing clinical status and progress in persons with severe and persistent mental illness. Editor spotlight. Lloyd et al., Treatment outcomes in schizophrenia: qualitative study of the views of family carers. Recently, a group of experts has developed a cognitive remediation group therapy approach called Integrated Neurocognitive Therapy (INT), which includes exercises to improve the MATRICS (Measurement and Treatment Research to Improve Cognition in Schizophrenia) neuro- and social-cognitive domains. Current research and development of new treatments for schizophrenia The Pharmaceutical Journal 11 FEB 2011 In this science article, Mark Ashton and Adam Todd examine the pathophysiology of schizophrenia, current treatments on the market and research into new treatments Response to medications vary. Department of Health. Most participants chose to be interviewed at home, but approximately 20% chose to come to the University. Although knowledge gaps remain, evidence from this review indicates that there is a quantitative relationship between functional capacity and real-world outcomes in individuals with schizophrenia. ‘It's great for it to be diagnosed, to be put on your medication and you're safe’ [C41]. Therefore, assessing social anxiety symptoms and its associated factors was significant to early intervention and management of schizophrenia patients in Ethiopia. For example, where a carer identified that the person they cared for experienced ongoing difficulties with engaging in physical activity, or that they wished the person they cared for could have the energy to engage in physical activity, this was interpreted as the carer indicating that being able to engage in physical activity was an important outcome, and hence it was coded within the ‘physical activity’ category. The recovery literature draws attention to the importance of recognising a broad array of outcome domains in schizophrenia treatment, highlighting the relevance of improved social and domestic functioning, alongside subjective wellbeing, optimism and empowerment (e.g. Data collectors randomly recruited 423 schizophrenic patients by using the systematic sampling technique. 3.759 Impact Factor. Table 1 lists these outcomes, and their sub-categories, and the proportion of interviews in which they occurred (using the conventions: ‘few’ for 2–10% (n = 1–4), ‘some’ for 12–24% (n = 5–10), ‘many’ for 25–50% (n = 11–21), and ‘most’ for >50% (n = 22–42)). Stubbs B, Firth J, Berry A, Schuch FB, Rosenbaum S, Gaughran F, Veronesse N, Williams J, Craig T, Yung AR, Vancampfort D. How much physical activity do people with schizophrenia engage in? After the final coding, the number of interviews in which each category occurred was calculated. Exploring the value of educating carers in ways to cope with poor insight in the person for whom they care, could be another important target for future work. Scott D, Happell B. This review addresses decision-making abilities of people with schizophrenia in both treatment and research contexts. The prevalence of social anxiety symptoms was 36.2% (95% CI: 31.50, 40.80). As treatment-resistant diseases become more common, more research will be needed in … He can rationalise…although he hears the voices he has a sense of reality. ’ [ C25 ] risk. Impact and interventions discussed were typically quite advanced in chronicity ( in most interviews i.e... Worker, psychiatric nurse and possibly a case manager to coordinate care missed out all his twenties and thirties maybe! Measuring the promise of recovery from serious mental illness similar to the existing domain engaging...... | Xiangning Chen | Travis Mize |... | Xiangning Chen | Travis Mize | |... 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